Buy Our Writers A Coffee

Subscription Amount. Min £2

A health worker counts antiretroviral drug tablets for a patient at The AIDS Support Organization (TASO) in the capital Kampala, Uganda, July 12, 2012. Photo AP

 

Uganda has kickstarted a trial for the injectable HIV drugs cabotegravir and rilpivirine. Researchers and those living with HIV say the trial will likely end pill fatigue, fight stigma, improve adherence and ensure patients get the right dosage.

The two drugs have been in use as tablets. The World Health Organization last year licensed their use as injectables.

While the two injectables already went through trials in Europe and North America, this will be the first time they are tested in an African population for efficacy and safety in an African health care system.

Uganda is one of three African countries, along with Kenya and South Africa, which got approval from the WHO to carry out the trials. However, Kenya and South Africa have yet to acquire approvals to start their trials, expected by the end of the year.

Uganda and Kenya will both have three trial sites and there will be two in South Africa, with a total of 512 participants -- 202 from Uganda, 160 from Kenya and 150 from South Africa.

Dr. Ivan Mambule, the lead project researcher at the Joint Clinical Research Center, says participants will need one injection every two months.

“We are going to choose participants who are already on ART [anti-retroviral treatment] and are stable on ART. And we will randomize them to either continue on their normal treatment, which is the pill that they’ve been taking, or to switch them to this injectable. The injection is on the buttock,” he expressed.

Uganda has 1.4 million people living with HIV/AIDS. Barbara Kemigisa who is living with HIV and founded the Pill Power Foundation working with rural women, says the injectable drugs will increase adherence to treatment and ensure people get the right dosage.

“One of the things that affects adherence is the fact that people have to hide medicine. In the village, people are hiding medicine in the kitchen roof, in trees, in bushes, in a baby’s shoe…If someone is wrapping the medicine in like five plastic bags and digs a hole in the garden and keeps the medicine there, by the time someone is taking that medicine, it’s no longer medicine, it's poison,” Kemigisa points out.

Nicholas Niwagaba, who has worked with young people living with HIV welcomes the trial, saying it will reduce the pill burden and fight stigma.

“Young people feel like, this is a lot of pills to take. Those who are on the first line, they will have to take one tablet a day. There are those who are on second line and they have to take more than one pill and they have to take it in the morning and in the evening. And of course, this requires you to have actually a balanced diet which is really a challenge for most of young people especially those from vulnerable communities,” he says.

According to the WHO, there are 25.7 million people living with HIV in Africa. With only the pill currently available to manage the scourge, this injectable may come as a relief for people living with HIV/AIDS. - Halima Athumani, Voice of America

About IEA Media Ltd

Informer East Africa is a UK based diaspora Newspaper. It is a unique platform connecting East Africans at home and abroad through news dissemination. It is a forum to learn together, grow together and get entertained at the same time.

To advertise events or products, get in touch by info [at] informereastafrica [dot] com or call +447957636854.
If you have an issue or a story, get in touch with the editor through editor[at] informereastafrica [dot] com or call +447886544135.

We also accept donations from our supporters. Please click on "donate". Your donations will go along way in supporting the newspaper.

Get in touch

Our Offices

London, UK
+44 7886 544135
editor (@) informereastafrica.com
Slough, UK
+44 7957 636854
info (@) informereastafrica.com

Latest News

24
Jan2021

Microsoft admits it...

This combination of file photos created on November 5, 2020 shows the PlayStation logo (top) on dis...

03
Feb2021

Tech CEOs including...

Jeff Bezos. MANDEL NGAN/AFP via Getty Images Jeff Bezos will step down as Amazon CEO in Q3 2021, th...

08
Feb2021

Kenyan Woman’s Start...

Photo UNEP/YouTube An absolutely brilliant young woman in Kenya has started a company manufacturing...

22
Feb2021

Nigeria’s ‘Techprene...

As recently as 10 years ago, Africa’s technology industry was sparse. But as a result of advancement...

For Advertisement

Big Reach

Informer East Africa is one platform for all people. It is a platform where you find so many professionals under one umbrella serving the African communities together.

Very Flexible

We exist to inform you, hear from you and connect you with what is happening around you. We do this professionally and timely as we endeavour to capture all that you should never miss. Informer East Africa is simply news for right now and the future.

Quality News

We only bring to you news that is verified, checked and follows strict journalistic guidelines and standards. We believe in 1. Objective coverage, 2. Impartiality and 3. Fair play.

Banner & Video Ads

A banner & video advertisement from our sponsors will show up every once in a while. It keeps us and our writers coffee replenished.